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MOTS-C

Endurance & Metabolism

Metabolic regulation, insulin sensitivity improvement, and exercise mimetic effects.

Athletic Use Cases
Mitochondrial EfficiencyEndurance CapacityMetabolic FlexibilityAMPK Activation
WADA Status
Not Listed
Standard Dose
5mg - 10mg
Frequency
3-5x weekly
Half-Life
~1 hour

Athletic Mechanism of Action

Mitochondria-derived peptide that activates AMPK and FOXO1 to regulate glucose metabolism and act as an exercise mimetic.

For athletes, the primary value of MOTS-C lies in its ability to metabolic regulation, insulin sensitivity improvement, and exercise mimetic effects.. This mechanism is particularly relevant during high-volume training phases when tissue repair demand exceeds the body's natural recovery capacity.

Recovery Timeline

4–8 weeks for endurance improvements

Individual response varies based on injury severity, training load, and baseline health markers.

WADA Compliance Status

Not Listed Compounded

Limited human safety data. Well tolerated in animal models.

Always verify current WADA status with your sport's governing body before use in competition.

Research Evidence

Primary Study

https://pubmed.ncbi.nlm.nih.gov/25738459/

Clinical Protocol

Start a MOTS-C Protocol

Hatter Labs provides physician-supervised performance protocols with GMP-certified MOTS-C and comprehensive biomarker monitoring.

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Physician-Supervised Performance

Start Your Performance Protocol for MOTS-C

Hatter Labs provides physician-supervised performance protocols with GMP-certified compounds, biomarker testing, and personalized programs designed around your training goals.

HIPAA Compliant · GMP Certified · Physician Supervised